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Cannabidiol (Hemp extract) Suppositories
A cbd suppository is a solid dosage form that is inserted into the rectum (rectal suppository) where it dissolves or melts and exerts systemic effects. Suppositories are used to deliver both systemically and locally acting hemp extract.
Rectal administration of cannabidiol has many advantages over other routes. If the oral route is not allowed because of ingestion restrictions often required before and after surgery, or if the oral route is impaired due eg. vomiting, injury to the jaw or throat, or gastrointestinal difficulties, it is still possible to administer Cannabis rectally.
CBD suppositories help prevent drug degradation in the gastrointestinal tract and bypass first-pass metabolism in the liver. This allows the cannabinoids to reach the blood at much higher concentrations. In addition, the rectal administration method allows a greater proportion of CBD to ultimately reach the bloodstream. This form of administration provides much faster absorption than oral administration (about 10 minutes, on average). The rapidity and reliability of CBD suppositories and their absorption, combined with their circumvention of many ingestion and inhalation problems, make rectal applications an excellent addition to new and pre-existing therapeutic regimens.
With CBD suppositories, the initial effects will most often be noticed within 10-15 minutes after application, and these effects usually last 4 to 8 hours depending on the individual’s cannabis physiology and tolerance. However, there are several problems that can slow the absorption of CBD suppositories from the rectum to the bloodstream. Diarrhea, feces and tumors or cysts on the wall of the rectum can slow down or prevent the cannabinoids from reaching the rectal wall and being absorbed. Rectal dehydration can also significantly reduce the effectiveness of cannabis suppositories. Staying well hydrated by maintaining a healthy intake of water and electrolytes can prevent this. However, a specific medical condition may also cause rectal dehydration, in which case the solution may not be as simple.
In case of concern, health professionals should be consulted. CBD suppositories can be used to refine existing regimens for better effects. People who have been prevented from using cannabis because of inability to administer by ingestion or inhalation, can potentially benefit from CBD for the first time using suppositories.